Our company strives to maintain and improve every phase of our business and satisfy needs of our customers. All products at our site are available to be shipped - that means we have them in stock and can ship them to you within 3-5 business days after payment clearance.
- Product overview
One ampoule of 2 ml contains 1 g metamizole sodium (0.5 g/ml). One ampoule of 5 ml contains 2.5 g metamizole sodium (0.5 g/ml). One tablet contains 0.5 g metamizole sodium.
Analgin tablets are administered for the treatment of pains of various origin: toothache, headache, arthralgia, neuralgia, myalgia, milder visceral pains, dysmenorrhea, as an antipyretic in the complex therapy of inflammatory diseases of upper respiratory tract, infectious diseases. Analgin solution for injection is used in cases of acute and severe pain after surgical operations or traumas; pains due to tumors; renal and biliary colics and high temperature unaffected by other drugs.
Dosage and administration:
Solution for injection: administered intramuscularly. The single dose for all age groups is 8-16 mg/kg body weight according to the following scheme: 16-31 kg body weight - 250 mg Analgin (1/2 ml); 32-46 kg body weight - 500 mg Analgin (1 ml); 47-62 kg body weight - 500-750 mg Analgin (1-1.5 ml); and over 63 kg body weight - 750-1000 mg Analgin (1.5-2 ml). In persistent pain, the dose can be repeated in 6-8 hours. Maximal daily dose - 4.0 g Analgin. Tablets: dosage and duration of treatment must be determined according to the severity of the pain syndrome. The usual dose in adults is 250-500 mg (1/2 -1 tablet) 2 or 3 times daily. Maximal 24-hour dose is 3 g.
In children over 15 years it is administered at a dose of 250 mg, 2-3 times daily.
Analgin should not be administered longer than 3 days or in higher doses without consulting the attending physician.
Hypersensitivity to metamizole and other pyrazolone derivatives; acute hepatic porphyria; inborn glucose-6-phosphate dehydrogenase deficiency; severe renal or hepatic diseases; hematologic diseases (aplastic anemia, leucopenia and agranulocytosis); first and last trimester of pregnancy. It should be avoided in lactating or pregnant women due to the lack of studies on its safety. Parenteral administration is contraindicated in children under 1 year.
Analgin potentiates the analgesic and antipyretic action of non-steroid anti-inflammatory drugs. Analgin effects are potentiated by the tricyclic antidepressants; oral contraceptives; allopurinol; alcohol. Analgin decreases the activity of coumarin anticoagulants and plasma levels of cyclosporin. The enzyme inductors (barbiturates, glutethimide, phenylbutazone) reduce Analgin effects. Analgin potentiates the effects of CNS-inhibiting agents. Concomitant administration with chlorpromazine hides the risk of severe hypothermia. Analgin may be combined with buscolysin, Atropinum sulfuricum, codeine.
Prolonged administration very rarely may cause reactions of agranulocytosis, leucopenia or thrombocytopenia, proteinuria, interstitial nephritis. In sensitive patients, rashes, urticaria, Quincke’s edema, asthmatic attacks, and very rarely anaphylactic shock are possible. Red pigmentation of urine with acid pH is due to the metabolite rubazonic acid.
10 or 100 ampoules of 2 ml (1 g) solution for injection.
10 ampoules of 5 ml (2,5 g) solution for injection.
20 tablets of 0.5 g.
500 tablets of 0,5 g (50 blisters X 10 tablets).
Ampoules – on doctor’s prescription. Tablets – without prescription.