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- Product overview
Botox (onabotulinumtoxinA), also called botulinum toxin type A, is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.
Botox is also used to treat certain eye muscle conditions caused by nerve disorders. This includes uncontrolled blinking or spasm of the eyelids, and a condition in which the eyes do not point in the same direction.
Botox is also used to treat overactive bladder and incontinence (urine leakage) caused by nerve disorders such as spinal cord injury or multiple sclerosis. It is also used to prevent chronic migraine headaches in adults who have migraines for more than 15 days per month, each lasting 4 hours or longer. This medicine should not be used to treat a common tension headache.
Botox Cosmetic is used to temporarily lessen the appearance of facial wrinkles.
You should not use Botox if you have an infection in the area where the medicine will be injected. Botox should not be used to treat overactive bladder or incontinence if you have a current bladder infection or if you are unable to urinate (unless you routinely use a catheter).
The botulinum toxin contained in this medication can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving botulinum toxin injections, even for cosmetic purposes.
Call your doctor at once if you have a hoarse voice, drooping eyelids, vision problems, severe muscle weakness, loss of bladder control, or trouble breathing, talking, or swallowing. Some of these effects can occur up to several hours or several weeks after receiving a Botox injection.
Before I receive Botox
You should not receive Botox if you are allergic to botulinum toxin, or if you have:
an infection in the area where the medicine will be injected; or
(for overactive bladder and incontinence) if you have a current bladder infection or if you are unable to urinate and you do not routinely use a catheter.
To make sure Botox is safe for you, tell your doctor if you have:
amyotrophic lateral sclerosis (ALS, or "Lou Gehrig's disease");
a breathing disorder such as asthma or emphysema;
problems with swallowing;
facial muscle weakness (droopy eyelids, weak forehead, trouble raising your eyebrows);
a change in the normal appearance of your face;
if you have had or will have surgery (especially on your face);
if you have recently used a blood thinner (warfarin, Coumadin, and others) or been treated with an injectable antibiotic;
if you have ever received other botulinum toxin injections such as Dysport or Myobloc (especially in the last 4 months); or
if you have ever had a side effect after receiving a botulinum toxin in the past.
Botox is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.
It is not known whether Botox will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
Botox can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How is Botox given?
Botox injections should be given only by a trained medical professional, even when used for cosmetic purposes.
Botox is injected into a muscle. A doctor, nurse, or other healthcare provider will give you this injection. Doses should be spaced at least 3 months apart.
Your Botox injection may be given into more than one area at a time, depending on the condition being treated.
While receiving Botox injections for an eye muscle conditions, you may need to use eye drops, ointment, a special contact lens or other device to protect the surface of your eye. Follow your doctor's instructions.
If you are being treated for excessive sweating, shave your underarms about 24 hours before you will receive your injection. Do not apply underarm antiperspirants or deodorants for 24 hours before you receive the injection. Avoid exercise and hot foods or beverages within 30 minutes before the injection.
It may take up to 2 weeks after injection before neck muscle spasm symptoms begin to improve. You may notice the greatest improvement at 6 weeks after injection.
It may take only 1 to 3 days after injection before eye muscle spasm symptoms begin to improve. You may notice the greatest improvement at 2 to 6 weeks after injection.
The effects of a Botox injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin.
Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.
Using this medication more often than prescribed will not make it more effective and may result in serious side effects.